Update-Death Investigation
November 26, 2025 – San Diego County Sheriff’s Office officials report that they are releasing details following 
the death of 44-year-old Brandon Pleffner, who was in custody at the San Diego Central Jail (SDCJ). On Sunday, November 16, 2025, Sheriff's Homicide investigators were notified of Mr. Pleffner's passing while in custody at SDCJ.
On November 16, 2025, at around 7:05 a.m., Sheriff's Deputies at the SDCJ were performing their routine duties when they discovered Mr. Pleffner unresponsive inside his assigned cell. Upon observing the situation, the deputies immediately activated 9-1-1, requested additional assistance from the facility's medical staff, and began life saving measures.
Paramedics and the San Diego Fire Department assumed lifesaving measures upon their arrival. Despite their efforts, Mr. Pleffner was pronounced deceased at the detention facility at about 7:35 a.m.
Mr. Pleffner had been in Sheriff's custody since November 8, 2025, and was facing charges for shoplifting with priors.
The San Diego Sheriff's Office extends our sympathies to the Pleffner family and all those affected by his passing. A Sheriff's Family Liaison Officer will continue to support the family as they navigate through this difficult time.
The Citizens' Law Enforcement Review Board (CLERB) has been notified regarding the incident. As is the protocol for all in-custody deaths, the Sheriff's Homicide Unit responded and is conducting a thorough investigation to ensure all aspects of this incident are examined. The cause and manner of death will be determined by the Medical Examiner's Office.
Source: San Diego County Sheriff’s Office